Nanoparticles and Nanocomposites Group
Institute of Materials Science of Barcelona (ICMAB-CSIC)
The group has long experience in the synthesis of nanomaterials. Relevant to this project is the development of magnetic nanoparticles and nanocomposites for medical uses. For the past years the group has maintained a fruitful collaboration with partner 1 to explore neurorepair strategies by enhancing angiogenesis. Our know-how encompasses wet chemical synthesis using traditional methods, microwave-assisted synthesis or supercritical fluids as well as expertise in nanomaterials characterization including the characterization of nano-bio-interfaces. The Team is composed by a physicist, chemist and a pharmacist. We have previous experience in EU granted projects under the FP7: (Common Sense, 3DInvitroNPC, Cosymetcox).
Role in the project
Biomaterials (SPIONs and PLGA nanocapsules including fuorescent tags) synthesis, surface functionalization (PEG), materials characterization and secretome encapsulation.
Dr. Anna Roig
Anna Roig graduated in Physics and received a PhD in Materials Science from the Autonomous University of Barcelona. She completed her education at the KTH in Stockholm and at Northeastern University in Boston. She also spent over two years as a Seconded National Expert in Brussels at the EC-Research Directorate. At present, she is Research Professor at the Materials Science Institute of Barcelona, a center with a Severo Ochoa label of Excellence in Spain and with ample International recognition. She leads the Nanoparticles and Nanocomposites Group (www.icmab.es/nn). Her group interests focus on developing novel complex nanoparticles and understanding of their structuralfunctional properties including aspects related to nano-bio-interfaces. The synthesized nanomateriales are evaluated as drug delivery nanocarriers and contrast agents for imaging techniques. Her expertise in the field is well recognized internationally by the over 50 invited talks at conferences and in other
SUMMARY OF SCIENTIFIC ACTIVITIES:
Over 170 research papers (published in Science, JACS, ACS Nano, Adv Mater, Adv Funct Mater, Green Chem, Chem. Mater., Chem Comm, J Mater Chem, Acta- Biomaterialia, Nanomedicine:NBM, Langmuir, etc). 9 patents, (1 commercialized, 5 PCT, 3 Spanish).
Supervision of 14 PhD Theses (11 finalized, 4 UAB Best PhD Thesis awards). Participation in more than 42 National and collaborative International research projects, 13 as IP. H=35, approx. 4350 citations (May 2017)
Yajie Zhang, MSc
Irene Anton, MSc
List of relevant publications
Recent selected publications excluding those in collaboration with partner 1:
1) Yu, S.; González-Moragas, L.; Milla, M.; Kolovou, A.; Santarella-Mellwig, R.; Schwab, Y.; Laromaine*, A., Roig*, A., Bio-identity and fate of albumin-coated SPIONs evaluated in cells and by the C. elegans model. Acta Biomaterialia 2016, 43, 348.
2) Gonzalez-Moragas, L.; Maurer, L.; Harms, V.; Meyer, J.; Laromaine, A.*; Roig, A.*; Materials and toxicological approaches to study metal and metal-oxide nanoparticles in the model organism Caenorhabditis elegans, Mater. Horiz., 2017, Review Article
3) S.M. Yu, J.A. Hachtel, M.F. Chisholm, S.T .Pantelides, A. Laromaine*, A Roig*. Magnetic Gold Nanotriangles by Microwave Polyol Synthesis, Nanoscale 2015, 7, 14039
4) L. Gonzalez-Moragas, S.M. Yu, N. Murillo-Cremaes, A. Laromaine, A. Roig* Scale-up synthesis of iron oxide nanoparticles by microwave-assisted thermal decomposition. Chemical Engineering Journal. 2015, 281, 87
5) N. Murillo-Cremaes, A. M. Lopez-Periago, J. Saurina, A. Roig,* C. Domingo,*. Nanostructured silica-based drug delivery vehicles for hydrophobic and moisture sensitive drugs. The Journal of Supercritical Fluids 2013, 73, 34.